Monsanto's Roundup kills human cells

This puts a whole new spin on Monsanto's "Roundup Ready" line of GMO products...

http://www.environmentalhealthnews.org/ehs/news/roundup-weed-killer-is-t...

[excerpt]

Weed killer kills human cells. Study intensifies debate over 'inert' ingredients.
Used in yards, farms and parks throughout the world, Roundup has long been a top-selling weed killer. But now researchers have found that one of Roundup’s inert ingredients can kill human cells, particularly embryonic, placental and umbilical cord cells. The new findings intensify a debate about so-called “inerts” — the solvents, preservatives, surfactants and other substances that manufacturers add to pesticides. Nearly 4,000 inert ingredients are approved for use by the U.S. Environmental Protection Agency.

By Crystal Gammon
Environmental Health News

June 22, 2009

Used in yards, farms and parks throughout the world, Roundup has long been a top-selling weed killer. But now researchers have found that one of Roundup’s inert ingredients can kill human cells, particularly embryonic, placental and umbilical cord cells.

The new findings intensify a debate about so-called “inerts” — the solvents, preservatives, surfactants and other substances that manufacturers add to pesticides. Nearly 4,000 inert ingredients are approved for use by the U.S. Environmental Protection Agency.

Glyphosate, Roundup’s active ingredient, is the most widely used herbicide in the United States. About 100 million pounds are applied to U.S. farms and lawns every year, according to the EPA.

Until now, most health studies have focused on the safety of glyphosate, rather than the mixture of ingredients found in Roundup. But in the new study, scientists found that Roundup’s inert ingredients amplified the toxic effect on human cells—even at concentrations much more diluted than those used on farms and lawns.

One specific inert ingredient, polyethoxylated tallowamine, or POEA, was more deadly to human embryonic, placental and umbilical cord cells than the herbicide itself – a finding the researchers call “astonishing.”

“This clearly confirms that the [inert ingredients] in Roundup formulations are not inert,” wrote the study authors from France’s University of Caen. “Moreover, the proprietary mixtures available on the market could cause cell damage and even death [at the] residual levels” found on Roundup-treated crops, such as soybeans, alfalfa and corn, or lawns and gardens.

The research team suspects that Roundup might cause pregnancy problems by interfering with hormone production, possibly leading to abnormal fetal development, low birth weights or miscarriages.

Monsanto, Roundup’s manufacturer, contends that the methods used in the study don’t reflect realistic conditions and that their product, which has been sold since the 1970s, is safe when used as directed. Hundreds of studies over the past 35 years have addressed the safety of glyphosate.

“Roundup has one of the most extensive human health safety and environmental data packages of any pesticide that's out there,” said Monsanto spokesman John Combest. “It's used in public parks, it's used to protect schools. There's been a great deal of study on Roundup, and we're very proud of its performance.”
...

“The authorizations for using these Roundup herbicides must now clearly be revised since their toxic effects depend on, and are multiplied by, other compounds used in the mixtures,” Seralini’s team wrote.

Controversy about the safety of the weed killer recently erupted in Argentina, one of the world’s largest exporters of soy.

Last month, an environmental group petitioned Argentina’s Supreme Court, seeking a temporary ban on glyphosate use after an Argentine scientist and local activists reported a high incidence of birth defects and cancers in people living near crop-spraying areas. Scientists there also linked genetic malformations in amphibians to glysophate. In addition, last year in Sweden, a scientific team found that exposure is a risk factor for people developing non-Hodgkin lymphoma.

Inert ingredients are often less scrutinized than active pest-killing ingredients. Since specific herbicide formulations are protected as trade secrets, manufacturers aren’t required to publicly disclose them. Although Monsanto is the largest manufacturer of glyphosate-based herbicides, several other manufacturers sell similar herbicides with different inert ingredients.

The term “inert ingredient” is often misleading, according to Caroline Cox, research director of the Center for Environmental Health, an Oakland-based environmental organization. Federal law classifies all pesticide ingredients that don’t harm pests as “inert,” she said. Inert compounds, therefore, aren’t necessarily biologically or toxicologically harmless – they simply don’t kill insects or weeds.

Kemery said the EPA takes into account the inert ingredients and how the product is used, whenever a pesticide is approved for use. The aim, he said, is to ensure that “if the product is used according to labeled directions, both people’s health and the environment will not be harmed.” One label requirement for Roundup is that it should not be used in or near freshwater to protect amphibians and other wildlife.

But some inert ingredients have been found to potentially affect human health. Many amplify the effects of active ingredients by helping them penetrate clothing, protective equipment and cell membranes, or by increasing their toxicity. For example, a Croatian team recently found that an herbicide formulation containing atrazine caused DNA damage, which can lead to cancer, while atrazine alone did not.
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[more at link]

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P.S.

Note that back in the 1990s, the government had to pass a law to get the pesticide manufacturers to disclose the inert ingredients in their products!

http://www.mindfully.org/Pesticide/Court-Disclose-Inerts.htm

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And additional research shows that at levels for pesticide residuals left by application of pesticides permitted by law, Roundup is harmful as noted above--

http://www.sott.net/articles/show/209506-Roundup-Kills-More-Than-Weeds

[excerpt]
Alarming new research on the health hazards of Roundup weed killer is shining a harsh light on a regulatory process that was meant to protect us.

To protect our health, the U.S. Environmental Protection Agency (EPA) sets maximum legal residue levels for every pesticide, for dozens of crops. But a new study in the respected journal Toxicology has shown that, at low levels that are currently legal on our food, Roundup could cause DNA damage, endocrine disruption and cell death. The study, conducted by French researchers, shows glyphosate-based herbicides are toxic to human reproductive cells.

The potential real-life risks from this are infertility, low sperm count, and prostate or testicular cancer. But, "Symptoms could be so subtle, they would be easy to overlook," says Theo Colborn, president of The Endocrine Disruption Exchange. "Timing is of critical importance. If a pregnant woman were to be exposed early in gestation, it looks like these herbicides could have an effect during the sexual differentiation stage. They really lock in on testosterone." The bottom line is more research is needed before we can fully understand the effects of glyphosate exposure.

A Perfect Poison

The researchers' most disturbing findings were not only the cytotoxic and hormonal responses to low-dose exposures, but the fact that the "active" ingredient - glyphosate - had much less of a toxic impact alone than the branded chemical mixtures sold to homeowners and farmers nationwide.

Solvents and surfactants, legally considered "inert ingredients," are mixed with glyphosate in products such as Roundup weed killer to create chemical formulations that increase mobility and more direct access to the cells. "Those same factors that aid penetration into a plant, also aid penetration into the skin," says Vincent Garry, professor emeritus of pathology at the University of Minnesota. "These chemicals are designed to kill cells."

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P.S.S.

Sort of reminds one of the use of dispersants for an oil spill, eh?